Introduction:
Xofluza is a relatively new antiviral medication, approved by the FDA in 2018 for treating uncomplicated influenza in patients aged 12 years and above. With the onset of seasonal flu strikes, the need to know more about Xofluza and its use is increasing. This guide will explore Xofluza’s prescribing information, dosage, and side effects to help healthcare professionals make the best decision for their patients.
Prescribing Information:
Xofluza is a prescription medication that comes in a tablet form. It inhibits the cap-dependent endonuclease enzyme of influenza viruses by binding and blocking the active site, preventing influenza virus replication. The drug’s recommended dose depends on the patient’s weight; adults weighing more than or equal to 80 kg should take a single 40 mg tablet, and patients weighing less than 80 kg should take a single 20 mg or 40 mg tablet. Xofluza’s prescribing information highlights that patients should take it within the first 48 hours of the symptoms’ onset.
Dosage:
Xofluza’s dosage is crucial as it has a unique one-time-only dose. The drug’s dosage varies based on the patient’s weight, and it is a single dose in most cases. The dosage also depends on the severity of the flu, which can only be determined by healthcare professionals. It is imperative to highlight that Xofluza should not be taken for the prevention of influenza.
Side Effects:
Like any other medication, Xofluza comes with some side effects that must not be ignored. Some of the common Xofluza side effects include bronchitis, diarrhea, headache, nausea, sinusitis, and abdominal pain. These side effects are usually mild and go away on their own. However, if the side effects persist or worsen, patients are advised to contact their healthcare professional immediately.
Examples:
A 50-year-old male with uncomplicated influenza comes to the clinic within 24 hours of symptoms onset. After evaluating the patient, the healthcare professional prescribes Xofluza 40mg based on his weight, which is 85 kg. The patient takes the single dose, and the symptoms improve within two days. The patient did not experience any severe side effects.
Conclusion:
In conclusion, Xofluza has proven to be a helpful antiviral medication in treating uncomplicated influenza. It is crucial for healthcare professionals to understand the prescribing information, dosage, and the potential side effects of Xofluza before prescribing it to their patients. A unique aspect of Xofluza is its one-time-only dose, which, when used appropriately, has shown to reduce the duration of the flu symptoms. As with any medication, patients must follow their healthcare professional’s instructions regarding Xofluza’s safe and effective use.
