A Comprehensive Guide to Understanding Oxbryta Prescribing Information
Sickle cell disease affects millions of people around the world, with an estimated 100,000 people living with the condition in the United States alone. Oxbryta is a recently approved medication that has been proven to help manage sickle cell disease. However, it’s essential to understand the prescribing information before using any medication.
In this comprehensive guide, we’ll dive deep into the Oxbryta prescribing information to help you make informed decisions.
What is Oxbryta?
Oxbryta, also known as voxelotor, is a medication that helps manage sickle cell disease. It’s being prescribed to patients aged 12 and above and works by facilitating oxygen delivery. The medication increases the hemoglobin’s affinity for oxygen, thus improving oxygen delivery and reducing red blood cell sickling. It was approved by the FDA in November 2019, making it the first approved medication for many years.
Dosage and Administration of Oxbryta
The dosage prescribed for Oxbryta is dependent on body weight. The starting dosage is 1500mg once daily for patients weighing 40kg or more. For patients under 40kg, the doctor will adjust the dosage accordingly. Oxbryta tablets should be swallowed whole with water and taken at the same time each day. The medication can be taken with or without food and should not be crushed or split.
Contraindications of Oxbryta
Before starting any medication, it’s essential to know the contraindications. Oxbryta has a few, such as hypersensitivity, pregnancy, and lactation. The medication has not been studied in lactating women, and the impact of Oxbryta on the fetal development is not known.
Adverse Reactions that may occur while using Oxbryta
Adverse reactions are not uncommon when using any medication, and Oxbryta is not an exception. The most common side effects reported are headache, nausea, diarrhea, and rash. Patients are advised to report any adverse reactions to their doctors, and dosage adjustments may be made as necessary.
Drug Interactions with Oxbryta
Drug interactions are possible with Oxbryta, and patients should inform their doctors of any other medications they are taking. Patients are not to use the medication concurrently with hydroxyurea, as this may increase the risk of toxicities.
Conclusion
In conclusion, Oxbryta is a newly approved medication that has been proven to be effective in managing sickle cell disease. However, patients need to understand the prescribing information before using the medication. This guide provides an overview of the essential prescribing information that will help patients make informed decisions regarding Oxbryta. Patients are encouraged to discuss any questions or concerns with their healthcare providers before starting any medication.
