Everything You Need to Know About Oxlumo Prescribing Information
If you or a loved one has been diagnosed with Primary Hyperoxaluria Type 1 (PH1), you may have heard about the new medication Oxlumo. Oxlumo (lumasiran) is a revolutionary drug that has recently been approved by the US Food and Drug Administration (FDA) to treat PH1, a rare genetic disorder that causes the body to produce too much oxalate, leading to damage to the kidneys and other organs. In this blog post, we will provide an overview of Oxlumo prescribing information, including how it works, who it is meant for, and what the potential side effects are.
What is Oxlumo?
Oxlumo is a new medication that was approved by the FDA in November 2020 for the treatment of PH1. It is a RNA interference therapy that works by blocking the production of an enzyme called glycolate oxidase (GO), which is responsible for the overproduction of oxalate in people with PH1. By reducing the production of oxalate, Oxlumo can help prevent the formation of kidney stones and reduce the risk of kidney damage.
Who is Oxlumo meant for?
Oxlumo is indicated for the treatment of PH1 in adults and children of all ages. It is important to note that Oxlumo is not a cure for PH1 but can help manage the symptoms of the condition. Before prescribing Oxlumo, healthcare providers will need to perform a genetic test to confirm that the patient has the specific mutation associated with PH1.
How is Oxlumo administered?
Oxlumo is administered by subcutaneous injection once a month. The dosage is based on the patient’s weight and ranges from 0.15 mg/kg to 1 mg/kg. The injection is usually given by a healthcare professional but can be self-administered by the patient or their caregiver after proper training.
What are the potential side effects of Oxlumo?
Like any medication, Oxlumo can cause side effects. The most common side effects associated with Oxlumo are injection site reactions, including pain, redness, and swelling. Other potential side effects include fever, rash, and headache. In clinical trials, no serious adverse events were reported in patients who received Oxlumo.
Conclusion
If you or a loved one has been diagnosed with PH1, Oxlumo may be an effective treatment option to manage the symptoms of the condition. As with any medication, it is important to work closely with your healthcare provider to determine if Oxlumo is the right choice for you and to monitor any potential side effects. We hope that this overview of Oxlumo prescribing information has been helpful in providing you with a better understanding of this important new medication.
