Understanding the Benefits of Disease Modifying Therapy for MS Patients
Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. It damages the myelin sheath which surrounds the nerve fibers, causing a range of symptoms including difficulty with vision, coordination, and balance. While there is no cure for MS, disease-modifying therapies (DMTs) have been developed to slow its progression and manage the symptoms. In this blog, we will discuss the benefits of DMTs for MS patients and how they work.
What are Disease Modifying Therapies?
DMTs, as the name suggests, modify the disease course of MS. They do not cure MS, but they reduce the frequency and severity of relapses, limit the development of new lesions and, in some cases, slow the progression of the disease. DMTs work by altering the immune system’s response to MS, which in turn reduces the inflammation that leads to the destruction of myelin.
Types of DMTs
There are several types of DMTs available, which differ in their mode of action, route of administration, and frequency of dosing. These include:
Injectable DMTs
Injectable DMTs are given by injection. These include interferon beta-1a, interferon beta-1b, and glatiramer acetate. These drugs stimulate the immune system, creating a response that reduces inflammation, and slows the progression of MS.
Oral DMTs
Oral DMTs include dimethyl fumarate, fingolimod, and teriflunomide. These drugs are taken orally and work by reducing inflammation in the brain and spinal cord.
Infused or Injectable Immunomodulators
Infused or injectable immunomodulators include natalizumab and alemtuzumab. These drugs modify the immune system by targeting specific cells that cause inflammation. Natalizumab is given by infusion, and alemtuzumab is given by injection.
Benefits of DMTs
DMTs can reduce the frequency of relapses and slow the progression of MS. They also reduce the number and size of lesions in the brain and spinal cord. Over time, this can reduce disability and improve the quality of life for MS patients. DMTs can also help with symptom management, such as fatigue and depression.
Conclusion
DMTs are an important tool in the management of MS. They can help slow the progression of the disease, reduce the frequency of relapses, and improve the quality of life for MS patients. However, different DMTs work in different ways and may not be suitable for everyone. Therefore, it is essential that MS patients work closely with their healthcare provider to determine which DMT is right for them.
