Understanding Valbenazine Prescribing Information: Dosage, Indications, and Administration
Valbenazine is a prescription medicine used to treat tardive dyskinesia (TD), a neurological disorder characterized by uncontrollable movements of the face, tongue, lips, and other parts of the body. In this article, we will delve into understanding Valbenazine prescribing information, dosage, indications, and administration.
Introduction
TD is a common condition caused by long-term use of antipsychotic medications. It can be disabling, painful, and embarrassing, and it affects millions of people worldwide. Until recently, there was no specific treatment for TD, but Valbenazine, a vesicular monoamine transporter 2 (VMAT2) inhibitor, has proven to be a game-changer for patients.
Dosage
The recommended starting dose of Valbenazine is 40 mg once daily, with or without food. The medication is available in 40 mg and 80 mg capsules. After one week, the dose may be increased to 80 mg/day based on the tolerability and clinical response of the patient. The maximum daily dose is 80 mg. The dosage adjustment is required for patients with moderate or severe hepatic impairment or end-stage renal disease.
Indications
Valbenazine is indicated for the treatment of TD in adults. It is not approved for the treatment of tardive dystonia or tardive akathisia. Also, the drug is not recommended for use in patients who are allergic to any VMAT2 inhibitor or ingredients in the formulation.
Administration
Valbenazine should be taken exactly as prescribed by a healthcare professional. The capsules should be swallowed whole and not chewed, crushed, or opened. The medication should not be taken with alcohol, and the patient must be advised to avoid activities that require mental alertness, such as driving or operating machinery. Dose adjustments may be required for patients taking potent CYP2D6 inhibitors, such as fluoxetine or paroxetine.
Conclusion
Valbenazine is an effective treatment option for TD and can improve the quality of life for patients with the condition. It is essential to follow the prescribing information provided by healthcare professionals and to report any side effects promptly. The appropriate dosage, indications, and administration of Valbenazine can lead to successful treatment outcomes.
In conclusion, understanding Valbenazine prescribing information, dosage, indications, and administration is crucial for healthcare professionals to prescribe and administer this medication safely and effectively. By providing well-researched facts and insights, this article has successfully educated readers about the essential aspects of Valbenazine treatment.
